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GSG2 antibody (AA 323-352)

GSG2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3404 unconjugated
Catalog No. ABIN1882168
  • Target See all GSG2 Antibodies
    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
    Binding Specificity
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 323-352
    Reactivity
    • 23
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 25
    • 2
    Rabbit
    Clonality
    • 26
    • 1
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSG2 antibody is un-conjugated
    Application
    • 13
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.
    Clone
    RB3404
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Dai, Sultan, Taylor, Higgins: "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment." in: Genes & development, Vol. 19, Issue 4, pp. 472-88, (2005) (PubMed).

    Higgins: "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells." in: Gene, Vol. 267, Issue 1, pp. 55-69, (2001) (PubMed).

    Tanaka, Iguchi, Nakamura, Kohroki, de Carvalho, Nishimune: "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase." in: Molecular human reproduction, Vol. 7, Issue 3, pp. 211-8, (2001) (PubMed).

  • Target
    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
    Alternative Name
    Haspin GSG2 (GSG2 Products)
    Synonyms
    BcDNA:LD07633 antibody, CG40080 antibody, Dmel\\CG40080 antibody, haspin antibody, NV16901 antibody, HASPIN antibody, Haspin antibody, putative serine/threonine-protein kinase haspin homolog antibody, histone H3 associated protein kinase antibody, CG40080 gene product from transcript CG40080-RA antibody, uncharacterized LOC100122327 antibody, LOC552287 antibody, HASPIN antibody, Haspin antibody, LOC100122327 antibody
    Background
    Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3).
    Molecular Weight
    88495
    NCBI Accession
    NP_114171
    UniProt
    Q8TF76
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