ATP1A1
Reactivity: Rat
WB, ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Hara, Urayama, Kawakami, Nojima, Nagamune, Kojima, Ohta, Nagano, Nakao: "Primary structures of two types of alpha-subunit of rat brain Na+,K+,-ATPase deduced from cDNA sequences." in: Journal of biochemistry, Vol. 102, Issue 1, pp. 43-58, (1987) (PubMed).
Herrera, Emanuel, Ruiz-Opazo, Levenson, Nadal-Ginard: "Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications." in: The Journal of cell biology, Vol. 105, Issue 4, pp. 1855-65, (1987) (PubMed).
Shull, Greeb, Lingrel: "Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain." in: Biochemistry, Vol. 25, Issue 25, pp. 8125-32, (1987) (PubMed).
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.