CA2 antibody (C-Term)

Catalog No. ABIN1882068

Product Details anti-CA2 Antibody

Target: CA2 (Carbonic Anhydrase II (CA2))

Binding Specificity: AA 209-238, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the C-terminal region of human CA2.

Clone: RB18369

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CA2 antibody (ABIN1882068)

Fisher, Kovalevsky, Domsic, Mustyakimov, Silverman, McKenna, Langan: "Preliminary joint neutron and X-ray crystallographic study of human carbonic anhydrase II." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 65, Issue Pt 5, pp. 495-8, (2009) (PubMed).

Adamus, Karren: "Autoimmunity against carbonic anhydrase II affects retinal cell functions in autoimmune retinopathy." in: Journal of autoimmunity, Vol. 32, Issue 2, pp. 133-9, (2009) (PubMed).

Target Details for CA2

Target: CA2 (Carbonic Anhydrase II (CA2))

Alternative Name: CA2 (CA2 Products)

Background: CA2 is one of several (at least 7) isozymes of carbonic anhydrase. The protein catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.

Molecular Weight: 29246

NCBI Accession: NP_000058

UniProt: P00918