ZFP36L1 antibody (N-Term)

Catalog No. ABIN1882008

Product Details anti-ZFP36L1 Antibody

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Binding Specificity: AA 64-93, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36L1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZFP36L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the N-terminal region of human ZFP36L1.

Clone: RB40956

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ZFP36L1 antibody (ABIN1882008)

Hacker, Valchanova, Adams, Munz: "ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production." in: Growth factors (Chur, Switzerland), Vol. 28, Issue 3, pp. 178-90, (2010) (PubMed).

Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: "Multiple common variants for celiac disease influencing immune gene expression. ..." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, (2010) (PubMed).

Takahashi, Tada, Mihara: "RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta." in: Molecular bioSystems, Vol. 5, Issue 9, pp. 986-91, (2009) (PubMed).

Sinha, Dutta, Datta, Ghosh, Mukhopadhyay: "Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32610-8, (2009) (PubMed).

Cheng, Saito, Pisarev, Wada, Pisareva, Pestova, Gajda, Round, Kong, Lim, Nakamura, Svergun, Ito, Song: "Structural insights into eRF3 and stop codon recognition by eRF1." in: Genes & development, Vol. 23, Issue 9, pp. 1106-18, (2009) (PubMed).

Target Details for ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Alternative Name: ZFP36L1 (ZFP36L1 Products)

Background: This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

Molecular Weight: 36314

NCBI Accession: NP_001231627, NP_001231630, NP_004917

UniProt: Q07352