This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This VAMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human VAMP4.
VAMP4
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Sabra, Damcott, Fu, Ott, OConnell, Mitchell, Shuldiner: "Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish." in: Molecular genetics and metabolism, Vol. 85, Issue 2, pp. 133-9, (2005) (PubMed).
Hinners, Wendler, Fei, Thomas, Thomas, Tooze: "AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1." in: EMBO reports, Vol. 4, Issue 12, pp. 1182-9, (2003) (PubMed).
Target
VAMP4
(Vesicle-Associated Membrane Protein 4 (VAMP4))
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.