UBE2R2 antibody (AA 141-169)

Catalog No. ABIN1881967

Product Details anti-UBE2R2 Antibody

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Binding Specificity: AA 141-169

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2R2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBE2R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of human UBE2R2.

Clone: RB30672

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-UBE2R2 antibody (ABIN1881967)

Yoshida, Kato, Yokoi, Oguri, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nozawa, Yamada: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, (2010) (PubMed).

Oguri, Kato, Yokoi, Yoshida, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nozawa, Yamada: "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals." in: American journal of hypertension, Vol. 23, Issue 1, pp. 70-7, (2009) (PubMed).

Ferreira, ODonovan, Meng, Jones, Ruderfer, Jones, Fan, Kirov, Perlis, Green, Smoller, Grozeva, Stone, Nikolov, Chambert, Hamshere, Nimgaonkar, Moskvina, Thase, Caesar, Sachs, Franklin et al.: "Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder...." in: Nature genetics, Vol. 40, Issue 9, pp. 1056-8, (2009) (PubMed).

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for UBE2R2

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Alternative Name: UBE2R2 (UBE2R2 Products)

Synonyms: CDC34B antibody, E2-CDC34B antibody, UBC3B antibody, zgc:92307 antibody, UBE2R2 antibody, 1200003M11Rik antibody, Cdc34b antibody, Ubc3b antibody, cdc34b antibody, e2-cdc34b antibody, ubc3b antibody, ubiquitin conjugating enzyme E2 R2 antibody, ubiquitin-conjugating enzyme E2R 2 antibody, ubiquitin-conjugating enzyme E2R 2 pseudogene antibody, UBE2R2 antibody, ube2r2 antibody, LOC465050 antibody, Ube2r2 antibody

Background: Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Molecular Weight: 27166

NCBI Accession: NP_060281

UniProt: Q712K3