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UBE2L3 antibody (C-Term)

UBE2L3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal RB41666 unconjugated
Catalog No. ABIN1881966
  • Target See all UBE2L3 Antibodies
    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
    Binding Specificity
    • 15
    • 13
    • 12
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 106-135, C-Term
    Reactivity
    • 61
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 59
    • 1
    • 1
    Rabbit
    Clonality
    • 60
    • 1
    Polyclonal
    Conjugate
    • 28
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2L3 antibody is un-conjugated
    Application
    • 56
    • 32
    • 20
    • 13
    • 13
    • 12
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.
    Clone
    RB41666
    Isotype
    Ig Fraction
    Top Product
    Discover our top product UBE2L3 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Amidon, Hawley: "Oral bioperformance and 21st century dissolution." in: Molecular pharmaceutics, Vol. 7, Issue 5, pp. 1361, (2013) (PubMed).

    Fransen, Visschedijk, van Sommeren, Fu, Franke, Festen, Stokkers, van Bodegraven, Crusius, Hommes, Zanen, de Jong, Wijmenga, van Diemen, Weersma: "Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease." in: Human molecular genetics, Vol. 19, Issue 17, pp. 3482-8, (2010) (PubMed).

    Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: "Multiple common variants for celiac disease influencing immune gene expression. ..." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, (2010) (PubMed).

    Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).

    Han, Zheng, Cui, Sun, Ye, Hu, Xu, Cai, Huang, Zhao, Xie, Fang, Lu, Xu, Li, Pan, Deng, Zeng, Ye, Zhang, Wang, Hao, Ma, Zuo, Zhou, Du, Cheng, Yang, Shen, Li, Sheng, Zuo, Zhu, Gao, Zhang, Guo, Li et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus...." in: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, (2009) (PubMed).

  • Target
    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
    Alternative Name
    UBE2L3 (UBE2L3 Products)
    Synonyms
    E2-F1 antibody, L-UBC antibody, UBCH7 antibody, UbcM4 antibody, C79827 antibody, Ubce7 antibody, ube2l3 antibody, wu:fc22h11 antibody, zgc:86727 antibody, UBE2L3 antibody, ube2l3l antibody, wu:fb38h03 antibody, ubiquitin conjugating enzyme E2 L3 antibody, ubiquitin-conjugating enzyme E2L 3 antibody, ubiquitin-conjugating enzyme E2L 3a antibody, ubiquitin conjugating enzyme E2 L3 S homeolog antibody, ubiquitin-conjugating enzyme E2L 3b antibody, UBE2L3 antibody, Ube2l3 antibody, ube2l3a antibody, ube2l3.S antibody, ube2l3b antibody
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    17862
    NCBI Accession
    NP_001243284, NP_001243285, NP_003338
    UniProt
    P68036
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