TXN antibody (C-Term)
(1 reference)-
- Target See all TXN Antibodies
- TXN (Thioredoxin (TXN))
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Binding Specificity
- AA 66-94, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TXN antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B, M, Pig, Rb, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.
- Clone
- RB42816
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TXN Primary Antibody
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anti-Thioredoxin (TXN) (AA 1-105) antibody
TXN Reactivity: Human WB, ELISA, IP, IF Host: Mouse Monoclonal 2A7 unconjugated
anti-Thioredoxin (TXN) (AA 2-105) antibodyTXN Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal 3# unconjugated
anti-Thioredoxin (TXN) (AA 51-105) antibodyTXN Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-30), (N-Term) antibodyTXN Reactivity: Human WB Host: Rabbit Polyclonal RB5217 unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN Reactivity: Human FACS Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Thioredoxin (TXN) antibodyTXN Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 1H6H6 unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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-
: "Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity." in: Redox biology, Vol. 14, pp. 237-249, (2018) (PubMed).
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: "Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity." in: Redox biology, Vol. 14, pp. 237-249, (2018) (PubMed).
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- Target
- TXN (Thioredoxin (TXN))
- Alternative Name
- TXN (TXN Products)
- Background
- Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
- Molecular Weight
- 11737
- NCBI Accession
- NP_001231867, NP_003320
- UniProt
- P10599
- Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
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