TTPA antibody (AA 82-108)

Catalog No. ABIN1881957

Product Details anti-TTPA Antibody

Target: TTPA (Tocopherol (Alpha) Transfer Protein (TTPA))

Binding Specificity: AA 82-108

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTPA antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TTPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA.

Clone: RB42171

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TTPA antibody (ABIN1881957)

Wirth, Poletti, Aeschlimann, Yakandawala, Drosse, Osorio, Tohge, Fernie, Günther, Gruissem, Sautter: "Rice endosperm iron biofortification by targeted and synergistic action of nicotianamine synthase and ferritin." in: Plant biotechnology journal, Vol. 7, Issue 7, pp. 631-44, (2009) (PubMed).

Wright, Peters, Gunter, Moore, Lawson, Yeager, Weinstein, Snyder, Virtamo, Albanes: "Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk." in: Cancer research, Vol. 69, Issue 4, pp. 1429-38, (2009) (PubMed).

Fusco, Frattini, Pisani, Gellera, Della Giustina: "Isolated vitamin E deficiency mimicking distal hereditary motor neuropathy in a 13-year-old boy." in: Journal of child neurology, Vol. 23, Issue 11, pp. 1328-30, (2008) (PubMed).

Rotzoll, Scherling, Etzl, Stepan, Horn, Pöschl: "Immunohistochemical localization of alpha-tocopherol transfer protein and lipoperoxidation products in human first-trimester and term placenta." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 140, Issue 2, pp. 183-91, (2008) (PubMed).

Kara, Uzümcü, Uyguner, Rosti, Koçbaş, Ozmen, Kayserili: "Ataxia with vitamin E deficiency associated with deafness." in: The Turkish journal of pediatrics, Vol. 50, Issue 5, pp. 471-5, (2008) (PubMed).

Target Details for TTPA

Target: TTPA (Tocopherol (Alpha) Transfer Protein (TTPA))

Alternative Name: TTPA (TTPA Products)

Synonyms: ATTP antibody, AVED antibody, TTP1 antibody, alphaTTP antibody, TTP antibody, alpha-TTP antibody, alpha tocopherol transfer protein antibody, tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) antibody, tocopherol (alpha) transfer protein antibody, TTPA antibody, ttpa antibody, Ttpa antibody

Background: This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.

Molecular Weight: 31750

NCBI Accession: NP_000361

UniProt: P49638