TSPY-Like 2 antibody (AA 380-409)

Catalog No. ABIN1881953

Product Details anti-TSPY-Like 2 Antibody

Target: TSPY-Like 2 (TSPYL2)

Binding Specificity: AA 380-409

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPY-Like 2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TSPYL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human TSPYL2.

Clone: RB43626

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TSPY-Like 2 antibody (ABIN1881953)

Chai, Sarcevic, Mawson, Toh: "SET-related cell division autoantigen-1 (CDA1) arrests cell growth." in: The Journal of biological chemistry, Vol. 276, Issue 36, pp. 33665-74, (2001) (PubMed).

Eichmuller, Usener, Dummer, Stein, Thiel, Schadendorf: "Serological detection of cutaneous T-cell lymphoma-associated antigens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 2, pp. 629-34, (2001) (PubMed).

Target Details for TSPY-Like 2

Target: TSPY-Like 2 (TSPYL2)

Alternative Name: TSPYL2 (TSPYL2 Products)

Background: Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.

Molecular Weight: 79435

NCBI Accession: NP_071400

UniProt: Q9H2G4

Pathways: ER-Nucleus Signaling