This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TSPYL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human TSPYL2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Chai, Sarcevic, Mawson, Toh: "SET-related cell division autoantigen-1 (CDA1) arrests cell growth." in: The Journal of biological chemistry, Vol. 276, Issue 36, pp. 33665-74, (2001) (PubMed).
Eichmuller, Usener, Dummer, Stein, Thiel, Schadendorf: "Serological detection of cutaneous T-cell lymphoma-associated antigens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 2, pp. 629-34, (2001) (PubMed).
Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.