This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TSPYL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the C-terminal region of human TSPYL1.
TSPYL1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Vinci, Brauner, Tar, Rouba, Sheth, Sheth, Ravel, McElreavey, Bashamboo: "Mutations in the TSPYL1 gene associated with 46,XY disorder of sex development and male infertility." in: Fertility and sterility, Vol. 92, Issue 4, pp. 1347-50, (2009) (PubMed).
de Andrade, Peterson, Cunha, Moreira, Fattori, Saad, Costa: "Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster." in: Blood cells, molecules & diseases, Vol. 37, Issue 2, pp. 82-90, (2006) (PubMed).
Hering, Frade-Martinez, Bajanowski, Poets, Tschentscher, Riess: "Genetic investigation of the TSPYL1 gene in sudden infant death syndrome." in: Genetics in medicine : official journal of the American College of Medical Genetics, Vol. 8, Issue 1, pp. 55-8, (2006) (PubMed).
Wang, Yoon, Oh, Jeon, Kim, Kim, Byun, Yang, Kim, Kim, Yeom, Yoo, Kim, Kim: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, (2006) (PubMed).
Puffenberger, Hu-Lince, Parod, Craig, Dobrin, Conway, Donarum, Strauss, Dunckley, Cardenas, Melmed, Wright, Liang, Stafford, Flynn, Morton, Stephan: "Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 32, pp. 11689-94, (2004) (PubMed).
The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT).