This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TIMD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the C-terminal region of human TIMD4.
TIMD4
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
RMT4-54
PE
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Dorfman, Hornick, Shahsafaei, Freeman: "The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms." in: Human pathology, Vol. 41, Issue 10, pp. 1486-94, (2010) (PubMed).
Zhao, Xu, Wang, Liang, Qi, Liu, Guo, Zhang, Ma, Gao: "Increased expression of human T-cell immunoglobulin- and mucin-domain-containing molecule-4 in peripheral blood mononuclear cells from patients with system lupus erythematosus." in: Cellular & molecular immunology, Vol. 7, Issue 2, pp. 152-6, (2010) (PubMed).
Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
Cai, Hu, Cui, Li, Chen, Wu: "Association of TIM4 promoter polymorphism -1419G>A with childhood asthma in a Chinese Han population." in: Tissue antigens, Vol. 74, Issue 1, pp. 11-6, (2009) (PubMed).
Park, Hochreiter-Hufford, Ravichandran: "The phosphatidylserine receptor TIM-4 does not mediate direct signaling." in: Current biology : CB, Vol. 19, Issue 4, pp. 346-51, (2009) (PubMed).
Target
TIMD4
(T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
RGD1564516 antibody, MGC99322 antibody, TIMD4 antibody, B430010N18Rik antibody, TIM-4 antibody, Tim4 antibody, SMUCKLER antibody, TIM4 antibody, T-cell immunoglobulin and mucin domain containing 4 antibody, T-cell immunoglobulin and mucin domain containing 4 L homeolog antibody, T cell immunoglobulin and mucin domain containing 4 antibody, Timd4 antibody, TIMD4 antibody, timd4.L antibody
Background
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1 (By similarity).