TES antibody (N-Term)

Catalog No. ABIN1881876

Product Details anti-TES Antibody

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Binding Specificity: AA 41-70, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TES antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, C, Hs, Pig, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TES.

Clone: RB41857

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TES antibody (ABIN1881876)

Qiu, Zhu, Yuan, Yan, Yang, Kong: "Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer." in: Cancer science, Vol. 101, Issue 5, pp. 1255-60, (2010) (PubMed).

Gunduz, Gunduz, Beder, Nagatsuka, Fukushima, Sutcu, Delibas, Yamanaka, Shimizu, Nagai: "Downregulation of TESTIN and its association with cancer history and a tendency toward poor survival in head and neck squamous cell carcinoma." in: Archives of otolaryngology--head & neck surgery, Vol. 135, Issue 3, pp. 254-60, (2009) (PubMed).

Boëda, Briggs, Higgins, Garvalov, Fadden, McDonald, Way: "Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding." in: Molecular cell, Vol. 28, Issue 6, pp. 1071-82, (2007) (PubMed).

Target Details for TES

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Alternative Name: TES (TES Products)

Synonyms: TESS antibody, TESS-2 antibody, tess antibody, tess-2 antibody, zgc:92091 antibody, xtes antibody, TES antibody, DKFZp469E2320 antibody, D6Ertd352e antibody, Tes1 antibody, Tes2 antibody, testin2 antibody, Testin antibody, testin LIM domain protein antibody, testin LIM domain protein L homeolog antibody, testis derived transcript (3 LIM domains) antibody, testis derived transcript antibody, TES antibody, tes.L antibody, tes antibody, Tes antibody

Background: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of this gene.

Molecular Weight: 47996

NCBI Accession: NP_056456, NP_690042

UniProt: Q9UGI8