SIRPB1 antibody (N-Term)

Catalog No. ABIN1881809

Product Details anti-SIRPB1 Antibody

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Binding Specificity: AA 17-43, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRPB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human SIRPB1.

Clone: RB45115

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SIRPB1 antibody (ABIN1881809)

Hatherley, Graham, Turner, Harlos, Stuart, Barclay: "Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47." in: Molecular cell, Vol. 31, Issue 2, pp. 266-77, (2008) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Target Details for SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Alternative Name: SIRPB1 (SIRPB1 Products)

Synonyms: CD172b antibody, SIRP-BETA-1 antibody, SIRPB1 antibody, SIRPG antibody, signal regulatory protein beta 1 antibody, signal-regulatory protein beta-1 antibody, signal-regulatory protein beta-1 isoform 3 antibody, SIRPB1 antibody, LOC458036 antibody, LOC458430 antibody, LOC485809 antibody, LOC715912 antibody, LOC100458151 antibody

Background: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes (By similarity).

Molecular Weight: 43359

NCBI Accession: NP_001129316

UniProt: Q5TFQ8