SDCBP antibody (N-Term)

Catalog No. ABIN1881779

Product Details anti-SDCBP Antibody

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDCBP antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SDCBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SDCBP.

Clone: RB42325

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SDCBP antibody (ABIN1881779)

Sun, Sun, Chen, Liao, He, Wang, Chen, Hu, Qiu: "microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway." in: Stem cell research & therapy, Vol. 12, Issue 1, pp. 14, (2021) (PubMed).

Reithmair, Buschmann, Märte, Kirchner, Hagl, Kaufmann, Pfob, Chouker, Steinlein, Pfaffl, Schelling: "Cellular and extracellular miRNAs are blood-compartment-specific diagnostic targets in sepsis." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2403-2411, (2018) (PubMed).

Youn, Friesen, Kishimoto, Henne, Kurat, Ye, Ceccarelli, Sicheri, Kohlwein, McMahon, Andrews: "Dissecting BAR domain function in the yeast Amphiphysins Rvs161 and Rvs167 during endocytosis." in: Molecular biology of the cell, Vol. 21, Issue 17, pp. 3054-69, (2010) (PubMed).

Qian, Shi, Pang, Wu, Yu, Li, Wang, Zhou: "[Identification and expression of two new secretory proteins associated with prostate cancer]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 32, Issue 3, pp. 235-41, (2010) (PubMed).

Hwangbo, Kim, Lee, Lee: "Activation of the integrin effector kinase focal adhesion kinase in cancer cells is regulated by crosstalk between protein kinase Calpha and the PDZ adapter protein mda-9/Syntenin." in: Cancer research, Vol. 70, Issue 4, pp. 1645-55, (2010) (PubMed).

Beekman, Verhagen, Geijsen, Coffer: "Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output." in: Blood, Vol. 114, Issue 18, pp. 3917-27, (2009) (PubMed).

Sira, Yoshida, Takeuchi, Kashiwayama, Futatani, Kanegane, Sasahara, Ito, Mizuguchi, Imanaka, Miyawaki: "A novel immunoregulatory protein in human colostrum, syntenin-1, for promoting the development of IgA-producing cells from cord blood B cells." in: International immunology, Vol. 21, Issue 9, pp. 1013-23, (2009) (PubMed).

Target Details for SDCBP

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Alternative Name: SDCBP (SDCBP Products)

Synonyms: MDA-9 antibody, ST1 antibody, SYCL antibody, TACIP18 antibody, Sycl antibody, syntenin-1 antibody, mda-9 antibody, st1 antibody, sycl antibody, tacip18 antibody, MGC81274 antibody, syntenin antibody, wu:fc51c03 antibody, wu:fk31e01 antibody, zgc:55679 antibody, zgc:77716 antibody, sb:eu862 antibody, si:dkey-235k4.1 antibody, syndecan binding protein antibody, syndecan binding protein L homeolog antibody, syndecan binding protein (syntenin) 2 antibody, syndecan binding protein (syntenin) antibody, SDCBP antibody, Sdcbp antibody, sdcbp.L antibody, LOC732879 antibody, sdcbp2 antibody, sdcbp antibody

Background: The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Molecular Weight: 32444

NCBI Accession: NP_001007068, NP_001007069, NP_001007070, NP_001007071, NP_005616

UniProt: O00560