RBP4 antibody (N-Term)

Catalog No. ABIN1881735

Product Details anti-RBP4 Antibody

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Binding Specificity: AA 11-40, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBP4 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Hs, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human RBP4.

Clone: RB41668

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RBP4 antibody (ABIN1881735)

Wang, Yeh, Wang, Chen, Chuang, Ker, Lee: "Decreased retinol binding protein 4 concentrations are associated with cholesterol gallstone disease." in: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 109, Issue 6, pp. 422-9, (2010) (PubMed).

Liu, Wei, Wang, Zhu, Bao, Jia: "[Expression and regulation of retinol binding protein 4 mRNA in human adipose tissue in obese and type 2 diabetics]." in: Zhonghua yi xue za zhi, Vol. 90, Issue 18, pp. 1251-4, (2010) (PubMed).

Ku, Han, Ahn, Kwon, Koo, Kim, Min: "Resistance exercise did not alter intramuscular adipose tissue but reduced retinol-binding protein-4 concentration in individuals with type 2 diabetes mellitus." in: The Journal of international medical research, Vol. 38, Issue 3, pp. 782-91, (2010) (PubMed).

Giacomozzi, Ghirri, Lapolla, Bartoli, Scirè, Serino, Germani, Boldrini, Cianfarani: "Retinol-binding protein 4 in neonates born small for gestational age." in: Journal of endocrinological investigation, Vol. 33, Issue 4, pp. 218-21, (2010) (PubMed).

Target Details for RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: RBP4 (RBP4 Products)

Background: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Molecular Weight: 23010

NCBI Accession: NP_006735

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response