This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Rat Cebpd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of rat Cebpd.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Kageyama, Sasai, Nakanishi: "Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. cDNA cloning of a novel C/EBP-related factor." in: The Journal of biological chemistry, Vol. 266, Issue 23, pp. 15525-31, (1991) (PubMed).
Target
CEBPD
(CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages (By similarity).