Prolactin Receptor antibody (AA 147-179)

Catalog No. ABIN1881684

Product Details anti-Prolactin Receptor Antibody

Target: Prolactin Receptor (PRLR)

Binding Specificity: AA 147-179

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the Central region of human PRLR.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Prolactin Receptor antibody (ABIN1881684)

Kline, Rycyzyn, Clevenger: "Characterization of a novel and functional human prolactin receptor isoform (deltaS1PRLr) containing only one extracellular fibronectin-like domain." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 10, pp. 2310-22, (2002) (PubMed).

Hu, Meng, Dufau: "Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 41086-94, (2001) (PubMed).

Kline, Roehrs, Clevenger: "Functional characterization of the intermediate isoform of the human prolactin receptor." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35461-8, (2000) (PubMed).

Hu, Zhuang, Meng, Leondires, Dufau: "The human prolactin receptor gene structure and alternative promoter utilization: the generic promoter hPIII and a novel human promoter hP(N)." in: The Journal of clinical endocrinology and metabolism, Vol. 84, Issue 3, pp. 1153-6, (1999) (PubMed).

Boutin, Edery, Shirota, Jolicoeur, Lesueur, Ali, Gould, Djiane, Kelly: "Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 3, Issue 9, pp. 1455-61, (1990) (PubMed).

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR (PRLR Products)

Synonyms: hPRLrI antibody, PRL-R antibody, prlr antibody, PRLRb antibody, PRLR antibody, tprlr antibody, DKFZp469D061 antibody, RATPRLR antibody, AI987712 antibody, Pr-1 antibody, Pr-3 antibody, Prlr-rs1 antibody, wu:fj65c07 antibody, prolactin receptor antibody, prolactin receptor L homeolog antibody, prolactin receptor S homeolog antibody, prolactin receptor a antibody, PRLR antibody, prlr.L antibody, prlr.S antibody, PR antibody, prlr antibody, Prlr antibody, prlra antibody

Background: This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Molecular Weight: 69506

NCBI Accession: NP_000940, NP_001191243, NP_001191244, NP_001191245, NP_001191246, NP_001191247

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus