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Progesterone Receptor antibody (C-Term)

Name: Progesterone Receptor antibody (C-Term)
SKU: ABIN1881650
Price: 451 USD
Availability: InStock

PGR Reactivity: Human WB Host: Rabbit Polyclonal RB41475 unconjugated

PGR Antibody (C-term) (ABIN1881650 and ABIN2838815) western blot analysis in ZR-75-1 cell line lysates (35 μg/lane). (Progesterone Receptor antibody (C-Term))

1 image

(3 references)

Catalog No. ABIN1881650

Datasheet as PDF

Target See all Progesterone Receptor (PGR) Antibodies

Progesterone Receptor (PGR)
Binding Specificity
16

16

15

10

10

10

8

8

8

8

6

5

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 833-861, C-Term
Reactivity
206

40

37

16

15

8

6

6

5

3

3

2

1

1

1

1

1
Human
Host
145

65

1
Rabbit
Compatible Secondaries
Clonality
139

71

1
Polyclonal
Conjugate
125

15

10

9

6

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This Progesterone Receptor antibody is un-conjugated
Application
171

83

57

33

29

26

26

23

18

18

17

11

6

3

2

1

1

1

1

1
Western Blotting (WB)

Predicted Reactivity

M, Rb, Rat, Sh

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This PGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 833-861 amino acids from the C-terminal region of human PGR.

Clone

RB41475

Isotype

Ig Fraction

Top Product

Discover our top product PGR Primary Antibody
anti-Progesterone Receptor (PGR) (AA 1-110) antibody
PGR Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 5D10 unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 166-411) antibody
PGR Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 2E4B9 unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR Reactivity: Human, Rat, Mouse, Monkey WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 1-250) antibody
PGR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 501-600) antibody
PGR Reactivity: Human WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro), FACS Host: Rabbit Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer190) antibody
PGR Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer294) antibody
PGR Reactivity: Human, Rat, Mouse, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer400) antibody
PGR Reactivity: Human, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 483-571) antibody
PGR Reactivity: Human IHC, StM Host: Mouse Monoclonal PGR-2694 unconjugated

Application Notes

WB: 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Van Belle, Van Calster, Brouckaert, Vanden Bempt, Pintens, Harvey, Murray, Naume, Wiedswang, Paridaens, Moerman, Amant, Leunen, Smeets, Drijkoningen, Wildiers, Christiaens, Vergote, Van Huffel, Neven: "Qualitative assessment of the progesterone receptor and HER2 improves the Nottingham Prognostic Index up to 5 years after breast cancer diagnosis." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 28, Issue 27, pp. 4129-34, (2010) (PubMed).

Geradts, Bean, Bentley, Barry: "The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features." in: Cancer investigation, Vol. 28, Issue 9, pp. 969-77, (2010) (PubMed).

Tang, Wang, Hicks, Wang, Schiffhauer, McMahon, Yang, Shayne, Huston, Skinner, Griggs, Lyman: "A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer." in: Cancer investigation, Vol. 28, Issue 9, pp. 978-82, (2010) (PubMed).
Target

Progesterone Receptor (PGR)

Alternative Name

PGR (PGR Products)

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

Molecular Weight

98981

NCBI Accession

NP_000917, NP_001189403, NP_001258091

UniProt

P06401

Pathways

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration