PGBD3 antibody (N-Term)

Catalog No. ABIN1881648

Product Details anti-PGBD3 Antibody

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Binding Specificity: AA 21-49, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGBD3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PGBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human PGBD3.

Clone: RB42444

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PGBD3 antibody (ABIN1881648)

Sarkar, Sim, Hong, Hogan, Fraser, Robertson, Collins: "Molecular evolutionary analysis of the widespread piggyBac transposon family and related \domesticated\" sequences."" in: Molecular genetics and genomics : MGG, Vol. 270, Issue 2, pp. 173-80, (2003) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for PGBD3

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Alternative Name: PGBD3 (PGBD3 Products)

Synonyms: PGBD3 antibody, piggyBac transposable element derived 3 antibody, ERCC excision repair 6, chromatin remodeling factor antibody, PGBD3 antibody, ERCC6 antibody

Background: The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene overlaps with the ERCC6 gene on chromosome 10, and pseudogenes of this locus have been found on chromosomes 4, 5 and 12.

Molecular Weight: 67595

NCBI Accession: NP_001263988, NP_736609

UniProt: Q8N328

Pathways: Chromatin Binding