OPCML antibody (AA 172-200)

Catalog No. ABIN1881594

Product Details anti-OPCML Antibody

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Binding Specificity: AA 172-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPCML antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This OPCML antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human OPCML.

Clone: RB41749

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-OPCML antibody (ABIN1881594)

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for OPCML

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Alternative Name: OPCML (OPCML Products)

Synonyms: IGLON1 antibody, OBCAM antibody, OPCM antibody, 2900075O15Rik antibody, 3732419F12 antibody, AI844366 antibody, B930023M13Rik antibody, C230027C17 antibody, Gm181 antibody, Obcam antibody, opioid binding protein/cell adhesion molecule like antibody, opioid binding protein/cell adhesion molecule-like antibody, OPCML antibody, Opcml antibody

Background: This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 38008

NCBI Accession: NP_001012393, NP_002536

UniProt: Q14982