NSF antibody (C-Term)

Catalog No. ABIN1881589

Product Details anti-NSF Antibody

Target: NSF (N-Ethylmaleimide-Sensitive Factor (NSF))

Binding Specificity: AA 668-696, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSF antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Ha, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-696 amino acids from the C-terminal region of human NSF.

Clone: RB41933

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-NSF antibody (ABIN1881589)

Hamza, Zabetian, Tenesa, Laederach, Montimurro, Yearout, Kay, Doheny, Paschall, Pugh, Kusel, Collura, Roberts, Griffith, Samii, Scott, Nutt, Factor, Payami: "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease." in: Nature genetics, Vol. 42, Issue 9, pp. 781-5, (2010) (PubMed).

Parashuraman, Madan, Mukhopadhyay: "NSF independent fusion of Salmonella-containing late phagosomes with early endosomes." in: FEBS letters, Vol. 584, Issue 6, pp. 1251-6, (2010) (PubMed).

Saus, Brunet, Armengol, Alonso, Crespo, Fernández-Aranda, Guitart, Martín-Santos, Menchón, Navinés, Soria, Torrens, Urretavizcaya, Vallès, Gratacòs, Estivill: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, (2010) (PubMed).

Simón-Sánchez, Schulte, Bras, Sharma, Gibbs, Berg, Paisan-Ruiz, Lichtner, Scholz, Hernandez, Krüger, Federoff, Klein, Goate, Perlmutter, Bonin, Nalls, Illig, Gieger, Houlden, Steffens, Okun et al.: "Genome-wide association study reveals genetic risk underlying Parkinson's disease...." in: Nature genetics, Vol. 41, Issue 12, pp. 1308-12, (2009) (PubMed).

Target Details for NSF

Target: NSF (N-Ethylmaleimide-Sensitive Factor (NSF))

Alternative Name: NSF (NSF Products)

Background: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

Molecular Weight: 82594

NCBI Accession: NP_006169

UniProt: P46459