NFE2L3 antibody (C-Term)

Catalog No. ABIN1881578

Product Details anti-NFE2L3 Antibody

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Binding Specificity: AA 666-694, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE2L3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NFE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-694 amino acids from the C-terminal region of human NFE2L3.

Clone: RB41576

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-NFE2L3 antibody (ABIN1881578)

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Zhang, Kobayashi, Yamamoto, Hayes: "The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 3195-210, (2009) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Target Details for NFE2L3

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Alternative Name: NFE2L3 (NFE2L3 Products)

Synonyms: NRF3 antibody, Nrf3 antibody, nuclear factor, erythroid 2 like 3 antibody, nuclear factor, erythroid derived 2, like 3 antibody, nuclear factor, erythroid 2-like 3 antibody, NFE2L3 antibody, Nfe2l3 antibody

Background: This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

Molecular Weight: 76154

NCBI Accession: NP_004280

UniProt: Q9Y4A8