MPDU1 antibody (C-Term)

Catalog No. ABIN1881550

Product Details anti-MPDU1 Antibody

Target: MPDU1 (Mannose-P-Dolichol Utilization Defect 1 (MPDU1))

Binding Specificity: AA 219-247, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPDU1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MPDU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the C-terminal region of human MPDU1.

Clone: RB42402

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-MPDU1 antibody (ABIN1881550)

Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, (2010) (PubMed).

Hosgood, Menashe, He, Chanock, Lan: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).

Shen, Vermeulen, Rajaraman, Menashe, He, Chapman, Yeager, Thomas, Burdett, Hutchinson, Yuenger, Chanock, Lan: "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." in: Environmental and molecular mutagenesis, Vol. 50, Issue 4, pp. 285-90, (2009) (PubMed).

Hosgood, Menashe, Shen, Yeager, Yuenger, Rajaraman, He, Chatterjee, Caporaso, Zhu, Chanock, Zheng, Lan: "Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway." in: Carcinogenesis, Vol. 29, Issue 10, pp. 1938-43, (2008) (PubMed).

Target Details for MPDU1

Target: MPDU1 (Mannose-P-Dolichol Utilization Defect 1 (MPDU1))

Alternative Name: MPDU1 (MPDU1 Products)

Background: This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants.

Molecular Weight: 26638

NCBI Accession: NP_004861

UniProt: O75352