MMP26 antibody (AA 96-125)

Catalog No. ABIN1881547

Product Details anti-MMP26 Antibody

Target: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Binding Specificity: AA 96-125

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP26 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.

Clone: RB41665

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-MMP26 antibody (ABIN1881547)

Liu, Cao, Li, Wu, Wang: "GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts." in: Reproductive biology and endocrinology : RB&E, Vol. 8, pp. 5, (2010) (PubMed).

de Amorim, da Silveira, Queiroz, Galvão, de Souza, de Almeida Freitas: "Matrilysins may not predict the metastatic potential in squamous cell carcinoma of the tongue." in: Acta odontologica Scandinavica, Vol. 68, Issue 4, pp. 228-31, (2010) (PubMed).

Target Details for MMP26

Target: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Alternative Name: MMP26 (MMP26 Products)

Synonyms: matrix metallopeptidase 26 antibody, MMP26 antibody

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

Molecular Weight: 29708

NCBI Accession: NP_068573

UniProt: Q9NRE1