This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MKI67IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-260 amino acids from the C-terminal region of human MKI67IP.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Byeon, Li, Song, Gronenborn, Tsai: "Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67." in: Nature structural & molecular biology, Vol. 12, Issue 11, pp. 987-93, (2006) (PubMed).
Li, Byeon, Ju, Tsai: "Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions." in: Journal of molecular biology, Vol. 335, Issue 1, pp. 371-81, (2003) (PubMed).
Takagi, Sueishi, Saiwaki, Kametaka, Yoneda: "A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25386-91, (2001) (PubMed).
This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.