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LONP1 antibody (AA 389-418)

LONP1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB40823 unconjugated
Catalog No. ABIN1881504
  • Target See all LONP1 Antibodies
    LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))
    Binding Specificity
    • 15
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 389-418
    Reactivity
    • 42
    • 26
    • 19
    Human, Mouse
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LONP1 antibody is un-conjugated
    Application
    • 31
    • 17
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    B, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
    Clone
    RB40823
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LONP1 Primary Antibody
  • Application Notes
    WB: 1:2000. WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Merra, Lago, Ricci, Antuzzi, Gasbarrini, Gasbarrini, Ghirlanda: "Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman." in: Case reports in gastroenterology, Vol. 2, Issue 3, pp. 474-8, (2011) (PubMed).

    Chen, Suzuki, Wu: "Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA." in: Nucleic acids research, Vol. 36, Issue 4, pp. 1273-87, (2008) (PubMed).

    Bayot, Basse, Lee, Gareil, Pirotte, Bulteau, Friguet, Reboud-Ravaux: "Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors." in: Biochimie, Vol. 90, Issue 2, pp. 260-9, (2008) (PubMed).

    Bogenhagen, Rousseau, Burke: "The layered structure of human mitochondrial DNA nucleoids." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).

    Xue, Zhu, Mao: "[Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells]." in: Nan fang yi ke da xue xue bao = Journal of Southern Medical University, Vol. 27, Issue 6, pp. 870-4, (2007) (PubMed).

  • Target
    LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))
    Alternative Name
    LONP1 (LONP1 Products)
    Synonyms
    PRSS15 antibody, prss15 antibody, fc64d11 antibody, wu:fc64d11 antibody, LON antibody, LONP antibody, LonHS antibody, PIM1 antibody, hLON antibody, 1200017E13Rik antibody, Prss15 antibody, Lon antibody, lon peptidase 1, mitochondrial antibody, ATP-dependent Lon protease antibody, LONP1 antibody, lonp1 antibody, Lonp1 antibody, PIM1 antibody
    Background
    This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.
    Molecular Weight
    106489
    NCBI Accession
    NP_001263408, NP_001263409, NP_004784
    UniProt
    P36776
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