LIG4 antibody (N-Term)
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- Target See all LIG4 Antibodies
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
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Binding Specificity
- AA 239-267, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LIG4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This LIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the N-terminal region of human LIG4.
- Clone
- RB40331
- Isotype
- Ig Fraction
- Top Product
- Discover our top product LIG4 Primary Antibody
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anti-Ligase IV, DNA, ATP-Dependent (LIG4) (C-Term) antibody
LIG4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 612-911) antibodyLIG4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibodyLIG4 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 275-324) antibodyLIG4 Reactivity: Human, Horse, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibodyKO Validated LIG4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 802-911) antibodyLIG4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2D2 unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibodyLIG4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (Center) antibodyLIG4 Reactivity: Human, Cow, Dog WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibodyLIG4 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 1-911) antibodyLIG4 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
- Alternative Name
- LIG4 (LIG4 Products)
- Synonyms
- zgc:165595 antibody, lig4 antibody, DNA LIGASE IV antibody, LIG4 antibody, lig4-A antibody, 5830471N16Rik antibody, tiny antibody, DNL4 antibody, ligase IV, DNA, ATP-dependent antibody, DNA ligase 4 antibody, ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining antibody, DNA ligase IV antibody, ligase IV, DNA, ATP-dependent L homeolog antibody, lig4 antibody, LIG4 antibody, LOC100212302 antibody, CpipJ_CPIJ005161 antibody, PTRG_09982 antibody, MCYG_05151 antibody, LOC657210 antibody, ATLIG4 antibody, lig4.L antibody, Lig4 antibody
- Background
- Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
- Molecular Weight
- 103971
- NCBI Accession
- NP_001091738, NP_002303, NP_996820
- UniProt
- P49917
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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