This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LGALS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the Central region of human LGALS7.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Demers, Rose, Grosset, Biron-Pain, Gaboury, Siegel, St-Pierre: "Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells." in: The American journal of pathology, Vol. 176, Issue 6, pp. 3023-31, (2010) (PubMed).
Park, Chang, Cho: "Induction of matrix metalloproteinase-9 by galectin-7 through p38 MAPK signaling in HeLa human cervical epithelial adenocarcinoma cells." in: Oncology reports, Vol. 22, Issue 6, pp. 1373-9, (2009) (PubMed).
Demers, Couillard, Giglia-Mari, Magnaldo, St-Pierre: "Increased galectin-7 gene expression in lymphoma cells is under the control of DNA methylation." in: Biochemical and biophysical research communications, Vol. 387, Issue 3, pp. 425-9, (2009) (PubMed).
Saussez, Cludts, Capouillez, Mortuaire, Smetana, Kaltner, André, Leroy, Gabius, Decaestecker: "Identification of matrix metalloproteinase-9 as an independent prognostic marker in laryngeal and hypopharyngeal cancer with opposite correlations to adhesion/growth-regulatory galectins-1 and -7." in: International journal of oncology, Vol. 34, Issue 2, pp. 433-9, (2009) (PubMed).
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19.