This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KCNK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human KCNK6.
KCNK6
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
FITC
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Sebastiani, Solovieff, Hartley, Milton, Riva, Dworkis, Melista, Klings, Garrett, Telen, Ashley-Koch, Baldwin, Steinberg: "Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study." in: American journal of hematology, Vol. 85, Issue 1, pp. 29-35, (2009) (PubMed).
Goldstein, Bayliss, Kim, Lesage, Plant, Rajan: "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels." in: Pharmacological reviews, Vol. 57, Issue 4, pp. 527-40, (2005) (PubMed).
Mhatre, Li, Chen, Yost, Smith, Kindler, Lalwani: "Genomic structure, cochlear expression, and mutation screening of KCNK6, a candidate gene for DFNA4." in: Journal of neuroscience research, Vol. 75, Issue 1, pp. 25-31, (2003) (PubMed).
Goldstein, Bockenhauer, OKelly, Zilberberg: "Potassium leak channels and the KCNK family of two-P-domain subunits." in: Nature reviews. Neuroscience, Vol. 2, Issue 3, pp. 175-84, (2001) (PubMed).
Target
KCNK6
(Potassium Channel Subfamily K Member 6 (KCNK6))
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Background
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq].