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HIST2H3A antibody (C-Term)

HIST2H3A Reactivity: Human WB Host: Rabbit Polyclonal RB41556 unconjugated
Catalog No. ABIN1881419
  • Target See all HIST2H3A Antibodies
    HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
    Binding Specificity
    • 15
    • 6
    • 2
    • 1
    AA 108-136, C-Term
    Reactivity
    • 16
    • 1
    • 1
    Human
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    This HIST2H3A antibody is un-conjugated
    Application
    • 15
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    B, M, Rat, C, Zf, X, E, D, Pig, Rb
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HIST2H3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human HIST2H3A.
    Clone
    RB41556
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HIST2H3A Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Neumann, Hancock, Buning, Routh, Chapman, Somers, Owen-Hughes, van Noort, Rhodes, Chin: "A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).

    Hurd, Bannister, Halls, Dawson, Vermeulen, Olsen, Ismail, Somers, Mann, Owen-Hughes, Gout, Kouzarides: "Phosphorylation of histone H3 Thr-45 is linked to apoptosis." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16575-83, (2009) (PubMed).

    Yuan, Pu, Zhang, Lou: "Histone H3-K56 acetylation is important for genomic stability in mammals." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 11, pp. 1747-53, (2009) (PubMed).

    Chang, Zhang, Beezhold, Bhatia, Zhao, Chen, Castranova, Shi, Chen: "Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer." in: Journal of hepatology, Vol. 50, Issue 2, pp. 323-33, (2009) (PubMed).

    Kobza, Sarath, Zempleni: "Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3." in: BMB reports, Vol. 41, Issue 4, pp. 310-5, (2008) (PubMed).

  • Target
    HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
    Alternative Name
    HIST2H3A (HIST2H3A Products)
    Synonyms
    H3/n antibody, H3/o antibody, histone cluster 2 H3 family member a antibody, HIST2H3A antibody
    Background
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy. [provided by RefSeq].
    Molecular Weight
    15388
    NCBI Accession
    NP_001005464, NP_001116847, NP_066403
    UniProt
    Q71DI3
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