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HIST2H2AC antibody (AA 18-46)

HIST2H2AC Reactivity: Human WB Host: Rabbit Polyclonal RB41799 unconjugated
Catalog No. ABIN1881417
  • Target See all HIST2H2AC Antibodies
    HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
    Binding Specificity
    • 6
    • 5
    • 4
    • 2
    AA 18-46
    Reactivity
    • 21
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    This HIST2H2AC antibody is un-conjugated
    Application
    • 16
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Rat, B, X, M, C, Pr, Zf, D
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
    Clone
    RB41799
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HIST2H2AC Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ishibashi, Dryhurst, Rose, Shabanowitz, Hunt, Ausió: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." in: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).

    Karaczyn, Cheng, Buzard, Hartley, Esposito, Kasprzak: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." in: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).

    Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

  • Target
    HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
    Alternative Name
    HIST2H2AC (HIST2H2AC Products)
    Synonyms
    HIST2H2AC antibody, H2A antibody, H2A-GL101 antibody, H2A/q antibody, H2AFQ antibody, H2a-613b antibody, RGD1560965 antibody, histone cluster 1, H2A, IV antibody, histone cluster 2 H2A family member c antibody, histone cluster 2, H2ac antibody, HIST1H2A4 antibody, HIST2H2AC antibody, Hist2h2ac antibody
    Background
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.
    Molecular Weight
    13988
    NCBI Accession
    NP_003508
    UniProt
    Q16777
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