HERC3 antibody (N-Term)

Catalog No. ABIN1881409

Product Details anti-HERC3 Antibody

Target: HERC3 (Hect Domain and RLD 3 (HERC3))

Binding Specificity: AA 51-77, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.

Clone: RB40596

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for HERC3

Target: HERC3 (Hect Domain and RLD 3 (HERC3))

Alternative Name: HERC3 (HERC3 Products)

Synonyms: 5730409F18Rik antibody, AI646603 antibody, mKIAA0032 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 3 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 3 L homeolog antibody, probable E3 ubiquitin-protein ligase HERC3 antibody, hect domain and RLD 3 antibody, HERC3 antibody, herc3.L antibody, herc3 antibody, LOC100539754 antibody, LOC100563151 antibody, Herc3 antibody

Background: HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).

Molecular Weight: 117188

NCBI Accession: NP_001258531, NP_055421

UniProt: Q15034