HEG1 antibody (C-Term)

Catalog No. ABIN1881407

Product Details anti-HEG1 Antibody

Target: HEG1 (HEG Homolog 1 (HEG1))

Binding Specificity: AA 691-717, C-Term

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEG1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DANRE heg antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 691-717 amino acids from the C-terminal region of DANRE heg.

Clone: RB42579

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HEG1 antibody (ABIN1881407)

Kleaveland, Zheng, Liu, Blum, Tung, Zou, Sweeney, Chen, Guo, Lu, Zhou, Kitajewski, Affolter, Ginsberg, Kahn: "Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway." in: Nature medicine, Vol. 15, Issue 2, pp. 169-76, (2009) (PubMed).

Mably, Mohideen, Burns, Chen, Fishman: "heart of glass regulates the concentric growth of the heart in zebrafish." in: Current biology : CB, Vol. 13, Issue 24, pp. 2138-47, (2003) (PubMed).

Target Details for HEG1

Target: HEG1 (HEG Homolog 1 (HEG1))

Alternative Name: heg (HEG1 Products)

Background: Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions.

Molecular Weight: 105529

NCBI Accession: NP_998133

UniProt: Q6R8J2

Pathways: Cell-Cell Junction Organization