GSTP1 antibody (AA 97-126)

Catalog No. ABIN1881393

Product Details anti-GSTP1 Antibody

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Binding Specificity: AA 97-126

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human GSTP1.

Clone: RB20807

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50. IHC: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GSTP1 antibody (ABIN1881393)

Cho, Eom, Kim, Kim, Lee, Kong: "Glutathione-S-transferase genotypes influence the risk of chemotherapy-related toxicities and prognosis in Korean patients with diffuse large B-cell lymphoma." in: Cancer genetics and cytogenetics, Vol. 198, Issue 1, pp. 40-6, (2010) (PubMed).

Kanai, Yoshioka, Tanaka, Nagayama, Matsumoto, Nishimura, Niimi, Teramukai, Takahashi, Mori, Kitano, Ishiguro, Yanagihara, Chiba, Fukushima, Matsuda: "Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy." in: Cancer epidemiology, Vol. 34, Issue 2, pp. 189-93, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Target Details for GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Alternative Name: GSTP1 (GSTP1 Products)

Synonyms: DFN7 antibody, FAEES3 antibody, GST3 antibody, GSTP antibody, PI antibody, GST-P antibody, Gst3 antibody, Gstp antibody, Gstp2 antibody, gst-Pi antibody, GstpiB antibody, glutathione S-transferase P-like antibody, glutathione S-transferase pi 1 antibody, glutathione S-transferase pi 1 L homeolog antibody, glutathione S-transferase, pi 1 antibody, LOC100739163 antibody, GSTP1 antibody, Gstp1 antibody, LOC100861197 antibody, gstp1.L antibody

Background: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Molecular Weight: 23356

NCBI Accession: NP_000843

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin