GLUD2 antibody (N-Term)

Catalog No. ABIN1881376

Product Details anti-GLUD2 Antibody

Target: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Binding Specificity: AA 75-103, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUD2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.

Clone: RB42527

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GLUD2 antibody (ABIN1881376)

Spanaki, Zaganas, Kleopa, Plaitakis: "Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16748-56, (2010) (PubMed).

Plaitakis, Latsoudis, Kanavouras, Ritz, Bronstein, Skoula, Mastorodemos, Papapetropoulos, Borompokas, Zaganas, Xiromerisiou, Hadjigeorgiou, Spanaki: "Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset." in: European journal of human genetics : EJHG, Vol. 18, Issue 3, pp. 336-41, (2010) (PubMed).

Target Details for GLUD2

Target: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Alternative Name: GLUD2 (GLUD2 Products)

Synonyms: GDH2 antibody, GLUDP1 antibody, GLUTAMATE DEHYDROGENASE 2 antibody, T2I1.150 antibody, T2I1_150 antibody, glutamate dehydrogenase 2 antibody, glutamate dehydrogenase 2 antibody, glutamate dehydrogenase antibody, GLUD2 antibody, GDH2 antibody, NP_RS03950 antibody

Background: The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

Molecular Weight: 61434

NCBI Accession: NP_036216

UniProt: P49448

Pathways: Synaptic Membrane