GEMIN4 antibody (N-Term)

Catalog No. ABIN1881369

Product Details anti-GEMIN4 Antibody

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Binding Specificity: AA 273-301, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.

Clone: RB41821

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GEMIN4 antibody (ABIN1881369)

Clague, Lippman, Yang, Hildebrandt, Ye, Lee, Wu: "Genetic variation in MicroRNA genes and risk of oral premalignant lesions." in: Molecular carcinogenesis, Vol. 49, Issue 2, pp. 183-9, (2010) (PubMed).

Kim, Choi, Jin, Kang, Choi, Jeon, Lee, Kim, Kim, Kim, Son, Jung, Park: "Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study." in: Molecular carcinogenesis, Vol. 49, Issue 10, pp. 913-21, (2010) (PubMed).

Wilker, Baccarelli, Suh, Vokonas, Wright, Schwartz: "Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes." in: Environmental health perspectives, Vol. 118, Issue 7, pp. 943-8, (2010) (PubMed).

Ye, Wang, Gu, Yang, Lin, Ajani, Wu: "Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk." in: Cancer prevention research (Philadelphia, Pa.), Vol. 1, Issue 6, pp. 460-9, (2009) (PubMed).

Target Details for GEMIN4

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Alternative Name: GEMIN4 (GEMIN4 Products)

Synonyms: HC56 antibody, HCAP1 antibody, HHRF-1 antibody, p97 antibody, 4932415L08Rik antibody, AU015359 antibody, im:7143815 antibody, wu:fc41c09 antibody, zgc:110169 antibody, GEMIN4 antibody, RGD1563715 antibody, gem nuclear organelle associated protein 4 antibody, gem (nuclear organelle) associated protein 4 antibody, GEMIN4 antibody, Gemin4 antibody, gemin4 antibody

Background: The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Molecular Weight: 120037

NCBI Accession: NP_056536

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization