This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FBXO43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-694 amino acids from the C-terminal region of human FBXO43.
Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (Probable).