EPH Receptor B6 antibody (AA 503-530)

Catalog No. ABIN1881301

Product Details anti-EPH Receptor B6 Antibody

Target: EPH Receptor B6 (EPHB6)

Binding Specificity: AA 503-530

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B6 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: H, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Ephb6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-530 amino acids from the Central region of mouse Ephb6.

Clone: RB40565

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-EPH Receptor B6 antibody (ABIN1881301)

Islam, Loizides, Fialkovich, Grand, Montgomery: "Developmental expression of Eph and ephrin family genes in mammalian small intestine." in: Digestive diseases and sciences, Vol. 55, Issue 9, pp. 2478-88, (2010) (PubMed).

Lieben, Benn, Ajibade, Stockmans, Moermans, Hediger, Peng, Christakos, Bouillon, Carmeliet: "Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis." in: Bone, Vol. 47, Issue 2, pp. 301-8, (2010) (PubMed).

Chou, Perez-Garcia, Kroll, OLeary: "Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex." in: Nature neuroscience, Vol. 12, Issue 11, pp. 1381-9, (2009) (PubMed).

Target Details for EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Alternative Name: Ephb6 (EPHB6 Products)

Background: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).

Molecular Weight: 110107

NCBI Accession: NP_001139823, NP_031706

UniProt: O08644

Pathways: RTK Signaling, Hormone Transport