ENPP3 antibody (C-Term)

Catalog No. ABIN1881297

Product Details anti-ENPP3 Antibody

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Binding Specificity: AA 814-843, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ENPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 814-843 amino acids from the C-terminal region of human ENPP3.

Clone: RB24586

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ENPP3 antibody (ABIN1881297)

Ono, Taniguchi, Higashi, Mita, Kajiwara, Yamaguchi, Tatsuno, Fukutomi, Tanimoto, Sekiya, Oshikata, Tsuburai, Tsurikisawa, Otomo, Maeda, Hasegawa, Miyazaki, Kumamoto, Akiyama: "CD203c expression on human basophils is associated with asthma exacerbation." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 483-489.e3, (2010) (PubMed).

Wolanczyk-Medrala, Barg, Gogolewski, Panaszek, Liebhart, Litwa, Medrala: "Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis." in: Annals of agricultural and environmental medicine : AAEM, Vol. 16, Issue 2, pp. 301-4, (2010) (PubMed).

Chirumbolo, Brizzi, Ortolani, Vella, Bellavite: "Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 58, Issue 11, pp. 755-64, (2009) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for ENPP3

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Alternative Name: ENPP3 (ENPP3 Products)

Synonyms: B10 antibody, CD203c antibody, NPP3 antibody, PD-IBETA antibody, PDNP3 antibody, Npp3 antibody, RB13-6 antibody, AI876438 antibody, ENPP3 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 3 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 3 L homeolog antibody, ENPP3 antibody, Enpp3 antibody, enpp3 antibody, enpp3.L antibody

Background: The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq].

Molecular Weight: 100124

NCBI Accession: NP_005012

UniProt: O14638

Pathways: Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity