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ENPP1 antibody (N-Term)

ENPP1 Reactivity: Human WB Host: Rabbit Polyclonal RB41733 unconjugated
Catalog No. ABIN1881296
  • Target See all ENPP1 Antibodies
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Binding Specificity
    • 15
    • 14
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 6-34, N-Term
    Reactivity
    • 42
    • 35
    • 11
    • 7
    • 4
    Human
    Host
    • 74
    • 5
    • 2
    Rabbit
    Clonality
    • 78
    • 3
    Polyclonal
    Conjugate
    • 21
    • 13
    • 12
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ENPP1 antibody is un-conjugated
    Application
    • 66
    • 35
    • 14
    • 14
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ENPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human ENPP1.
    Clone
    RB41733
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ENPP1 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ermakov, Rosenbaum, Malkin, Livshits: "Family-based study of association between ENPP1 genetic variants and craniofacial morphology." in: Annals of human biology, Vol. 37, Issue 6, pp. 754-66, (2010) (PubMed).

    Wang, Peng, Qu, Huang: "[Association and meta-analysis of ENPP1 K121Q with type 2 diabetes in Han Chinese.]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 32, Issue 8, pp. 808-16, (2010) (PubMed).

    Cruz, Valladares-Salgado, Garcia-Mena, Ross, Edwards, Angeles-Martinez, Ortega-Camarillo, de la Peña, Burguete-Garcia, Wacher-Rodarte, Ambriz, Rivera, Dartote, Peralta, Parra, Kumate: "Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City." in: Diabetes/metabolism research and reviews, Vol. 26, Issue 4, pp. 261-70, (2010) (PubMed).

    Moehlecke, Kramer, Leitão, Krahe, Balbosco, Azevedo, Gross, Canani: "[ENPP1 K121Q polymorphism and ischemic heart disease in diabetic patients]." in: Arquivos brasileiros de cardiologia, Vol. 94, Issue 2, pp. 157-61, 168-73, 159-63, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

  • Target
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Alternative Name
    ENPP1 (ENPP1 Products)
    Synonyms
    ENPP1 antibody, si:ch211-142e24.2 antibody, zgc:136238 antibody, ARHR2 antibody, M6S1 antibody, NPP1 antibody, NPPS antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, 4833416E15Rik antibody, AI428932 antibody, C76301 antibody, CD203c antibody, E-NPP1 antibody, Ly-41 antibody, Npps antibody, Pca antibody, Pca-1 antibody, Pdnp1 antibody, ttw antibody, twy antibody, Pc1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 L homeolog antibody, ENPP1 antibody, enpp1 antibody, enpp1.L antibody, Enpp1 antibody
    Background
    This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
    Molecular Weight
    104924
    NCBI Accession
    NP_006199
    UniProt
    P22413
    Pathways
    Regulation of Carbohydrate Metabolic Process
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