EBI3 antibody (C-Term)

Catalog No. ABIN1881277

Product Details anti-EBI3 Antibody

Target: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Binding Specificity: AA 153-181, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EBI3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EBI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the C-terminal region of human EBI3.

Clone: RB30602

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-EBI3 antibody (ABIN1881277)

Kempe, Heinz, Kokai, Devergne, Marx, Wirth: "Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques." in: The American journal of pathology, Vol. 175, Issue 1, pp. 440-7, (2009) (PubMed).

Krumbiegel, Anthogalidis-Voss, Markus, Zepp, Meyer: "Enhanced expression of IL-27 mRNA in human newborns." in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Vol. 19, Issue 6, pp. 513-6, (2008) (PubMed).

Poleganov, Bachmann, Pfeilschifter, Mühl: "Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: critical role of two kappaB binding sites in the human EBI3 promotor." in: Molecular immunology, Vol. 45, Issue 10, pp. 2869-80, (2008) (PubMed).

Carl, Bai: "IL27: its roles in the induction and inhibition of inflammation." in: International journal of clinical and experimental pathology, Vol. 1, Issue 2, pp. 117-23, (2008) (PubMed).

Target Details for EBI3

Target: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Alternative Name: EBI3 (IL-27b Products)

Synonyms: IL-27B antibody, IL27B antibody, EBI3 antibody, il-27rb antibody, si:dkey-97a13.4 antibody, EBI-3 antibody, IL-27 antibody, Epstein-Barr virus induced 3 antibody, Epstein-Barr virus induced gene 3 antibody, EBI3 antibody, ebi3 antibody, Ebi3 antibody

Target Type: Viral Protein

Background: This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Molecular Weight: 25396

NCBI Accession: NP_005746

UniProt: Q14213