DPEP1 antibody (N-Term)

Catalog No. ABIN1881269

Product Details anti-DPEP1 Antibody

Target: DPEP1 (Dipeptidase 1 (Renal) (DPEP1))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPEP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.

Clone: RB41566

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for DPEP1

Target: DPEP1 (Dipeptidase 1 (Renal) (DPEP1))

Alternative Name: DPEP1 (DPEP1 Products)

Synonyms: AI327012 antibody, MBD antibody, MBD1 antibody, MDP antibody, RDP antibody, dipeptidase 1 (renal) antibody, dipeptidase 1 antibody, DPEP1 antibody, Dpep1 antibody

Background: DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 [PubMed 2303490]).

Molecular Weight: 45674

NCBI Accession: NP_001121613, NP_004404

UniProt: P16444

Pathways: Inositol Metabolic Process