DIRC2 antibody (AA 202-229)

Catalog No. ABIN1881261

Product Details anti-DIRC2 Antibody

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Binding Specificity: AA 202-229

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIRC2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human DIRC2.

Clone: RB42515

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-DIRC2 antibody (ABIN1881261)

Bodmer, Eleveld, Kater-Baats, Janssen, Janssen, Weterman, Schoenmakers, Nickerson, Linehan, Zbar, van Kessel: "Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21)." in: Human molecular genetics, Vol. 11, Issue 6, pp. 641-9, (2002) (PubMed).

Bodmer, Janssen, Jonkers, van den Berg, Dijkhuizen, Debiec-Rychter, Schoenmakers, van Kessel: "Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints." in: Cancer genetics and cytogenetics, Vol. 136, Issue 2, pp. 95-100, (2002) (PubMed).

Target Details for DIRC2

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Alternative Name: DIRC2 (DIRC2 Products)

Synonyms: MGC80843 antibody, zgc:92095 antibody, rcc4 antibody, MGC69320 antibody, RCC4 antibody, disrupted in renal carcinoma 2 antibody, disrupted in renal carcinoma 2 L homeolog antibody, disrupted in renal carcinoma 2 (human) antibody, DIRC2 antibody, dirc2.L antibody, dirc2 antibody, Dirc2 antibody

Background: This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.

Molecular Weight: 52088

NCBI Accession: NP_116228

UniProt: Q96SL1