DDX19B antibody (N-Term)

Catalog No. ABIN1881254

Product Details anti-DDX19B Antibody

Target: DDX19B (DEAD (Asp-Glu-Ala-As) Box Polypeptide 19B (DDX19B))

Binding Specificity: AA 7-36, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX19B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DDX19B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human DDX19B.

Clone: RB41830

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-DDX19B antibody (ABIN1881254)

Collins, Karlberg, Lehtiö, Schütz, van den Berg, Dahlgren, Hammarström, Weigelt, Schüler: "The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10296-300, (2009) (PubMed).

von Moeller, Basquin, Conti: "The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner." in: Nature structural & molecular biology, Vol. 16, Issue 3, pp. 247-54, (2009) (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Target Details for DDX19B

Target: DDX19B (DEAD (Asp-Glu-Ala-As) Box Polypeptide 19B (DDX19B))

Alternative Name: DDX19B (DDX19B Products)

Synonyms: DBP5 antibody, DDX19 antibody, RNAh antibody, 2810457M08Rik antibody, 4921519L13Rik antibody, AW260119 antibody, MGC75870 antibody, DDX19B antibody, Zd10a antibody, ddx19 antibody, DEAD-box helicase 19B antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b antibody, ATP-dependent RNA helicase DDX19B antibody, DEAD (Asp-Glu-Ala-As) box polypeptide 19B antibody, DEAD-box helicase 19B S homeolog antibody, DDX19B antibody, Ddx19b antibody, ddx19b antibody, LOC100054938 antibody, LOC100075859 antibody, LOC100581804 antibody, ddx19b.S antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 53927

NCBI Accession: NP_001014449, NP_001014451, NP_001244101, NP_001244102, NP_001244103, NP_009173

UniProt: Q9UMR2