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COLQ antibody (C-Term)

COLQ Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB30589 unconjugated
Catalog No. ABIN1881222
  • Target See all COLQ Antibodies
    COLQ (AChE Q Subunit (COLQ))
    Binding Specificity
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 324-353, C-Term
    Reactivity
    • 29
    • 17
    • 10
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COLQ antibody is un-conjugated
    Application
    • 22
    • 15
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
    Clone
    RB30589
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Mihaylova, Müller, Vilchez, Salih, Kabiraj, DAmico, Bertini, Wölfle, Schreiner, Kurlemann, Rasic, Siskova, Colomer, Herczegfalvi, Fabriciova, Weschke, Scola, Hoellen, Schara, Abicht, Lochmüller: "Clinical and molecular genetic findings in COLQ-mutant congenital myasthenic syndromes." in: Brain : a journal of neurology, Vol. 131, Issue Pt 3, pp. 747-59, (2008) (PubMed).

    Schreiner, Hoppenz, Klaeren, Reimann, Woelfle: "Novel COLQ mutation 950delC in synaptic congenital myasthenic syndrome and symptomatic heterozygous relatives." in: Neuromuscular disorders : NMD, Vol. 17, Issue 3, pp. 262-5, (2007) (PubMed).

    Ishigaki, Nicolle, Krejci, Leroy, Koenig, Fardeau, Eymard, Hantaï: "Two novel mutations in the COLQ gene cause endplate acetylcholinesterase deficiency." in: Neuromuscular disorders : NMD, Vol. 13, Issue 3, pp. 236-44, (2003) (PubMed).

  • Target
    COLQ (AChE Q Subunit (COLQ))
    Alternative Name
    COLQ (COLQ Products)
    Synonyms
    EAD antibody, A130034K24Rik antibody, collagen like tail subunit of asymmetric acetylcholinesterase antibody, collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase antibody, COLQ antibody, Colq antibody
    Background
    This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    47766
    NCBI Accession
    NP_005668, NP_536799, NP_536800
    UniProt
    Q9Y215
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