CNTF antibody (AA 114-140)

Catalog No. ABIN1881219

Product Details anti-CNTF Antibody

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Binding Specificity: AA 114-140

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNTF antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CNTF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-140 amino acids from the Central region of human CNTF.

Clone: RB44449

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CNTF antibody (ABIN1881219)

Takahashi, Yokoji, Misawa, Hayashi, Hu, Deguchi: "A null mutation in the human CNTF gene is not causally related to neurological diseases." in: Nature genetics, Vol. 7, Issue 1, pp. 79-84, (1994) (PubMed).

Masiakowski, Liu, Radziejewski, Lottspeich, Oberthuer, Wong, Lindsay, Furth, Panayotatos: "Recombinant human and rat ciliary neurotrophic factors." in: Journal of neurochemistry, Vol. 57, Issue 3, pp. 1003-12, (1991) (PubMed).

Negro, Tolosano, Skaper, Martini, Callegaro, Silengo, Fiorini, Altruda: "Cloning and expression of human ciliary neurotrophic factor." in: European journal of biochemistry / FEBS, Vol. 201, Issue 1, pp. 289-94, (1991) (PubMed).

McDonald, Ko, Mismer, Smith, Collins: "Expression and characterization of recombinant human ciliary neurotrophic factor from Escherichia coli." in: Biochimica et biophysica acta, Vol. 1090, Issue 1, pp. 70-80, (1991) (PubMed).

Lam, Fuller, Miller, Kloss, Manthorpe, Varon, Cordell: "Sequence and structural organization of the human gene encoding ciliary neurotrophic factor." in: Gene, Vol. 102, Issue 2, pp. 271-6, (1991) (PubMed).

Target Details for CNTF

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Alternative Name: CNTF (CNTF Products)

Background: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.

Molecular Weight: 22931

NCBI Accession: NP_000605

UniProt: P26441

Pathways: JAK-STAT Signaling