Chloride Channel 5 antibody (N-Term)

Catalog No. ABIN1881207

Product Details anti-Chloride Channel 5 Antibody

Target: Chloride Channel 5 (CLCN5)

Binding Specificity: AA 15-41, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chloride Channel 5 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Pig, Rb, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human CLCN5.

Clone: RB42009

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Chloride Channel 5 antibody (ABIN1881207)

Smith, Lippiat: "Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3696-705, (2010) (PubMed).

Wellhauser, DAntonio, Bear: "ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 2, pp. 543-57, (2010) (PubMed).

Picollo, Malvezzi, Accardi: "Proton block of the CLC-5 Cl-/H+ exchanger." in: The Journal of general physiology, Vol. 135, Issue 6, pp. 653-9, (2010) (PubMed).

White: "On the position and value of those Lesions of the Brain which cause a rise of Temperature." in: The Journal of physiology, Vol. 12, Issue 3, pp. 233-298.3, (2007) (PubMed).

Target Details for Chloride Channel 5

Target: Chloride Channel 5 (CLCN5)

Alternative Name: CLCN5 (CLCN5 Products)

Background: This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 90785

NCBI Accession: NP_000075, NP_001121370, NP_001121371, NP_001269092

UniProt: P51795