This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CD3EAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human CD3EAP.
CD3EAP
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, (2010) (PubMed).
Vangsted, Klausen, Gimsing, Andersen, Abildgaard, Gregersen, Vogel: "A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support." in: Haematologica, Vol. 94, Issue 9, pp. 1274-81, (2009) (PubMed).
Nissen, Vogel, Nexø: "Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines." in: Anti-cancer drugs, Vol. 20, Issue 3, pp. 174-8, (2009) (PubMed).
Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).
Target
CD3EAP
(CD3e Molecule, epsilon Associated Protein (CD3EAP))
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.