CCKAR antibody (AA 228-257)

Catalog No. ABIN1881149

Product Details anti-CCKAR Antibody

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Binding Specificity: AA 228-257

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKAR antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human CCKAR.

Clone: RB40248

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CCKAR antibody (ABIN1881149)

Cong, Pricolo, Biancani, Behar: "Effects of cholesterol on CCK-1 receptors and caveolin-3 proteins recycling in human gallbladder muscle." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 299, Issue 3, pp. G742-50, (2010) (PubMed).

Park, Rew, Lee, Ki, Lee, Cheo, Kim, Noh, Joo, Kim, Choi: "Association of CCK(1) Receptor Gene Polymorphisms and Irritable Bowel Syndrome in Korean." in: Journal of neurogastroenterology and motility, Vol. 16, Issue 1, pp. 71-6, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, (2010) (PubMed).

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: CCKAR (CCKAR Products)

Synonyms: CCK-XL antibody, cck-a antibody, cck1-r antibody, cckar-A antibody, cckbr antibody, cckra antibody, CCKAR antibody, CCK-A antibody, CCK1-R antibody, CCKRA antibody, AW106902 antibody, Cck-ar antibody, CCK-AR antibody, cholecystokinin A receptor antibody, cholecystokinin A receptor L homeolog antibody, CCKAR antibody, cckar.L antibody, Cckar antibody

Background: This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.

Molecular Weight: 47841

NCBI Accession: NP_000721

UniProt: P32238

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour